Since opening in 2009, Arraystar Inc. has successfully provided services for hundreds of esteemed universities, hospitals, and research centers, including NIH, FDA, UCSD, Rockefeller University, Columbia University, University of Toronto, M. D. Anderson Cancer Center and many others.
Arraystar Epitranscriptomic Array
Transient Focal Ischemia Significantly Alters the m6A Epitranscriptomic Tagging of RNAs in the Brains. Chokkalla A K, et al. Stroke, 2019
m6A methylation of precursor-miR-320/RUNX2 controls osteogenic potential of bone marrow-derived mesenchymal stem cells. Yan G, et al. Molecular Therapy-Nucleic Acids, 2019
Arraystar LncRNA Array & Service
Defining the adult neural stem cell niche proteome identifies key regulators of adult neurogenesis. Kjell J, et al. Cell Stem Cell, 2020
Fibrogenic Activity of MECP2 is Regulated by Phosphorylation in Hepatic Stellate Cells. Moran-Salvador E, et al. Gastroenterology, 2019
A long noncoding RNA cluster-based genomic locus maintains proper development and visual function. Wang F,et al. Nucleic Acids Research, 2019
Loss of RNA-binding protein GRSF1 activates mTOR to elicit a proinflammatory transcriptional program. Noh J H, et al. Nucleic Acids Research, 2019
NKILA lncRNA promotes tumor immune evasion by sensitizing T cells to activation-induced cell death. Huang D, et al. Nature immunology, 2018
Long Non-coding RNA GMAN, Upregulated in Gastric Cancer Tissues, is Associated with Metastasis in Patients and Promotes Translation of Ephrin A1 by Competitively Binding GMAN-AS. Zhuo W, et al. Gastroenterology, 2018
GUARDIN is a p53-responsive long non-coding RNA that is essential for genomic stability. Hu W L, et al. Nature Cell Biology, 2018
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Arraystar circRNA Array & Service
Circular RNAs as biomarkers in liquid biopsy in colorectal cancer. Valladares-Ayerbes M, et al. Journal of Clinical Oncology, 2020
Circ-AKT3 inhibits clear cell renal cell carcinoma metastasis via altering miR-296-3p/E-cadherin signals. Xue D, et al. Molecular Cancer, 2019
circGSK3ß promotes metastasis in esophageal squamous cell carcinoma by augmenting ß-catenin signaling. Hu X, et al. Molecular Cancer, 2019
A Noncoding Regulatory RNAs Network Driven by Circ-CDYL Acts Specifically in the Early Stages Hepatocellular Carcinoma. Wei Y, et al. Hepatology, 2019
Circular RNA CircFndc3b modulates cardiac repair after myocardial infarction via FUS/VEGF-A axis. Garikipati V., et al. Nature Communications, 2019
FOXP1 circular RNA sustains mesenchymal stem cell identity via microRNA inhibition. Cherubini A, et al. Nucleic Acids Research, 2019
A Circular RNA Protects Dormant Hematopoietic Stem Cells from DNA Sensor cGAS-Mediated Exhaustion. Xia P, et al. Immunity, 2018
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nrStar™ tRNA PCR Array
DNA damage-induced cell death relies on SLFN11-dependent cleavage of distinct type II tRNAs. Li M, et al. Nature Structural & Molecular Biology, 2018
tRNA‐based prognostic score in predicting survival outcomes of lung adenocarcinomas. Kuang M, et al. International journal of cancer, 2018
nrStar™ Functional LncRNA PCR Array
LncRNA ZEB2-AS1 promotes pancreatic cancer cell growth and invasion through regulating the miR-204/HMGB1 axis. Gao H, et al. International journal of biological macromolecules, 2018
Saturated fatty acid alters embryonic cortical neurogenesis through modulation of gene expression in neural stem cells. Ardah MT, et al. The Journal of nutritional biochemistry, 2018
NuRNA™ mRNA PCR Array
CPT1A-mediated fatty acid oxidation promotes colorectal cancer cell metastasis by inhibiting anoikis. Wang Y, et al. Oncogene, 2018 (NuRNA™ Human Central Metabolism PCR Array)
Arraystar Gene Expression Array & Service
The Toxoplasma effector TEEGR promotes parasite persistence by modulating NF-κB signalling via EZH2. Braun L, et al. Nature microbiology, 2019
Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development. Guay C,et al. Cell metabolism, 2018
Osteoblast-secreted factors mediate dormancy of metastatic prostate cancer in the bone via activation of the TGFβRIII-p38MAPK-pS249/T252RB pathway. Yu-Lee L Y, et al. Cancer Research, 2018
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Arraystar piRNA Array & Service
Transcriptome‑wide piRNA profiling in human gastric cancer. Lin X, et al. Oncology reports, 2019
PIWIL3/OIP5-AS1/miR-367-3p/CEBPA feedback loop regulates the biological behavior of glioma cells. Liu X, et al. Theranostics, 2018
RASSF1C modulation of Piwi-interacting RNAs (piRNAs) in lung cancer.YG Amaar, et al.Cancer Research, 2015
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Arraystar LncPath™ Pathway Array Service
circRNA_100290 plays a role in oral cancer by functioning as a sponge of the miR-29 family. Chen L, et al. Oncogene, 2017
Identification and functional annotation of metabolism‐associated lnc RNA s and their related protein‐coding genes in gastric cancer. Mo X, et al. Molecular genetics & genomic medicine, 2018
circRNA_0084043 promote malignant melanoma progression via miR-153-3p/Snail axis. Luan W, et al. Biochemical and biophysical research communications, 2018
Detection and Analysis of the Hedgehog Signaling Pathway-Related Long Non-Coding RNA (lncRNA) Expression Profiles in Keloid. Huang H, et al. Medical Science Monitor, 2018
Global expression profiling of metabolic pathway‐related lncRNAs in human gastric cancer and the identification of RP11‐555H23. 1 as a new diagnostic biomarker. Mo X, et al. Journal of clinical laboratory analysis, 2018
Aberrantly expressed long noncoding RNAs are involved in ***-induced developing hippocampal neuronal apoptosis: a microarray related study.X Chen et al.Metabolic Brain Disease, 2016
Detection and Analysis of Wnt Pathway Related lncRNAs Expression Profile in Lung Adenocarcinoma. Chen J, et al. Pathology & Oncology Research, 2016
Decreased expression of long noncoding RNA MT1JP may be a novel diagnostic and predictive biomarker in gastric cancer. Yang J, et al. Int J Clin Exp Pathol, 2017
Expression of LOC285758, a potential long non-coding biomarker, is methylation-dependent and correlates with glioma malignancy grade. Matjasic A, et al. Radiology and Oncology, 2017
Arraystar T-UCR Array Service
Long Noncoding RNA uc.173 Promotes Renewal of the Intestinal Mucosa by Inducing Degradation of MicroRNA 195. Xiao L, et al. Gastroenterology, 2017
Noncoding Transcribed Ultraconserved Region (T-UCR) uc.261 Participates in Intestinal Mucosa Barrier Damage in Crohn's Disease. Qian X X, et al. inflammatory bowel diseases, 2016
Arraystar MeDIP-chip Service
MSC Transplantation Improves Osteopenia via Epigenetic Regulation of Notch Signaling in Lupus. Shiyu Liu, et al. Cell Metabolism, 2016
Long-term parental *** exposure of mice influences behavior and hippocampal DNA methylation of the offspring. Y Itzhak, et al. Molecular Psychiatry, 2014
TFIIS. h, a new target of p53, regulates transcription efficiency of pro-apoptotic bax gene. JM Liao, et al. Scientific Reports, 2016
Epigenetic inactivation of the CpG demethylase TET1 as a DNA methylation feedback loop in human cancers. Li L, et al. Scientific reports, 2016
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Arraystar hMeDIP-chip Service
TET3 Mediates Alterations in the Epigenetic Marker 5hmC and Akt Pathway in Steroid‐Associated Osteonecrosis. Zhao J, et al. Journal of Bone and Mineral Research, 2016
Arraystar RNA Sequencing Service
Profiling the microRNA signature of the peripheral sensory ganglia in experimental autoimmune encephalomyelitis (EAE). Friedman T N, et al. Journal of neuroinflammation, 2019
Patient-derived organoids model treatment response of metastatic gastrointestinal cancers. Vlachogiannis G, et al. Science, 2018
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Arraystar tRNA Sequencing Service
A rare codon-based translational program of cell proliferation. Guimaraes J C, et al. Genome Biology, 2020
Arraystar microRNA Sequencing Service
Complexity of the microRNA transcriptome of cow milk and milk-derived extracellular vesicles isolated via differential ultracentrifugation. Benmoussa A, et al. Journal of dairy science, 2019
Next-generation sequencing of the basal cell carcinoma miRNome and a description of novel microRNA candidates under neoadjuvant vismo***** therapy: an integrative molecular and surgical case study.Sand M, et al. Ann Oncol,2016
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Arraystar ChIP-sequencing Service
A conserved enhancer regulates Il9 expression in multiple lineages. Koh B, et al. Nature communications. 2018
The LINK-A lncRNA activates normoxic HIF1 [alpha] signalling in triple-negative breast cancer. Lin A,et al. Nature cell biology, 2016
Direct Transcriptional Effects of Apolipoprotein E. Veena Theendakara, et al. Neurobiology of Disease, 2016
Role for Dpy-30 in ES Cell-Fate Specification by Regulation of H3K4 Methylation within Bivalent Domains. Hao Jiang, et al. Cell, 2011
Arraystar (h)MeDIP-sequencing Service
Loss of Endometrial Plasticity in Recurrent Pregnancy Loss Emma S. Lucas,et al. Stem cells, 2016.
Differential DNA methylation of microRNAs within promoters, intergenic and intragenic regions of type 2 diabetic, pre-diabetic and non-diabetic individuals. C Pheiffer,et al. Clinical Biochemistry, 2016.
Genome-wide DNA methylation in mixed ancestry individuals with diabetes and prediabetes from South Africa.TE Matsha, et al. International Journal of Endocrinology, 2016
Dynamic interplay between locus-specific DNA methylation and hydroxymethylation regulates distinct biological pathways in prostate carcinogenesis. Shivani N,et al. Clinical Epigenetics, 2015
Parp inhibition prevents ten eleven translocase enzyme activation and hyperglycemia induced DNA demethylation. Dhliwayo N, et al. Diabetes, 2014.
Characterization of the DNA methylome and its interindividual variation in human peripheral blood monocytes. Hui Shen, et al. Epigenomics, 2013.
Heritable Transmission of Diabetic Metabolic Memory in Zebrafish Correlates With DNA Hypomethylation and Aberrant Gene Expression. Ansgar S. Olsen, et al. Diabetes, 2012.
Arraystar CLIP-sequencing Service
Intronic RNAs mediate EZH2 regulation of epigenetic targets. Sonia Guil, et al. Nature Structural & Molecular Biology, 2012
Real-Time qPCR Reagents and Kits
Synovial fluid-derived exosomal lncRNA PCGEM1 as biomarker for the different stages of osteoarthritis. Zhao Y, Xu J. International orthopaedics, 2018
Integrating lncRNAs and mRNAs expression profiles in terminal hindgut of fetal rats with anorectal malformations. Xiao H, et al. Pediatric surgery international, 2018
MicroRNA‑143‑3p contributes to the regulation of pain responses in collagen‑induced arthritis. Zhou L L, et al. Molecular medicine reports, 2018
miR-21 silencing ameliorates experimental autoimmune encephalomyelitis by promoting the differentiation of IL-10-producing B cells. Wang H, et al. Oncotarget, 2017
Long noncoding RNA HAS2‐AS1 mediates hypoxia‐induced invasiveness of oral squamous cell carcinoma. Zhu G, et al. Molecular Carcinogenesis, 2017
Mir-344b-1-3p targets Tlr2 and negatively regulates Tlr2 signaling pathway. Wu Y, et al. International Journal of COPD, 2017
Scutellarin suppresses human colorectal cancer metastasis and angiogenesis by targeting ephrinb2. Zhu P T, et al. Am J Transl Res, 2017
Plasma lncRNA GAS8-AS1 as a Potential Biomarker of Papillary Thyroid Carcinoma in Chinese Patients. Zhang D,et al. International Journal of Endocrinology, 2017
NADPH oxidase inhibitor improves outcome of mechanical reperfusion by suppressing hemorrhagic transformation. Tuo Y H, et al. Journal of neurointerventional surgery, 2017
NADPH oxidase inhibitor regulates microRNAs with improved outcome after mechanical reperfusion. Liu Z, Tuo Y H, et al. Journal of neurointerventional surgery, 2016
Anxiety-like behavior and dysregulation of miR-34a in triple transgenic mice of Alzheimer’s disease. Y.-L. Zhang, et al. Eur Rev Med Pharmacol Sci , 2016
Physiological and transcriptional responses of Nitrosomonas europaea to TiO2 and ZnO nanoparticles and their mixtures. Yu R, Wu J, Liu M, et al. Environmental Science and Pollution Research, 2016
Seq-Star™ NGS Solutions
Immunophenotyping and transcriptional profiling of in vitro cultured human adipose tissue derived stem cells. Mieczkowska A, et al. Scientific reports, 2018
circRNA_100290 plays a role in oral cancer by functioning as a sponge of the miR-29 family. Chen L, et al. Oncogene, 2017
Systematic identification and comparison of expressed profiles of lncRNAs and circRNAs with associated co-expression and ceRNA networks in mouse germline stem cells. Li X, Ao J, Wu J. Oncotarget, 2017
Integrative analysis for the role of long non-coding RNAs in radiation-induced mouse thymocytes responses. Hui Gao, et al. Acta Biochimica et Biophysica Sinica, 2016
LC-MS
Elongator and codon bias regulate protein levels in mammalian peripheral neurons. Goffena J, et al. Nature Communications, 2018