rtStar™ tRNA Pretreatment & First-Strand cDNA Synthesis Kit
Benefits
• Efficient removal of internal modifications of tRNAs to ensure the proceeding of reverse transcriptase during cDNA synthesis, whereas the regular cDNA synthesis method doesn’t have.
• Magnitudes of increase in tRNA detection sensitivity and quantification accuracy with the treated compared with untreated samples.
| Product Name | Catalog No. | Description | Size | Price |
|---|---|---|---|---|
| rtStar™ tRNA Pretreatment & First-Strand cDNA Synthesis Kit | AS-FS-004 | 12 reactions | $360.00 |
TRMT6-mediated tRNA m1A modification acts as a translational checkpoint of histone synthesis and facilitates colorectal cancer progression. Tao E, et al. Nature Cancer, 2025
PAX translocations remodel mitochondrial metabolism through altered leucine usage in rhabdomyosarcoma. Bhargab Kalita, et al. Cell, 2025
Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma. El-Hachem N, et al. Nature Cell Biology, 2024
Chemotherapeutic agents and leucine deprivation induce codon-biased aberrant protein production in cancer. Adva Kochavi, et al. Nucleic Acids Research, 2024
tRNA Ini CAT inhibits proliferation and promotes apoptosis of laryngeal squamous cell carcinoma cell. Shen Z, et al. Journal of Clinical Laboratory Analysis, 2021
Gene-Specific Control of tRNA Expression by RNA Polymerase II. Gerber A, et al. Molecular Cell, 2020
Quantitative tRNA-sequencing uncovers metazoan tissue-specific tRNA regulation. Pinkard O, et al. Nature Communications, 2020
tRNA-based prognostic score in predicting survival outcomes of lung adenocarcinomas. Kuang M, et al. International journal of cancer, 2019
DNA damage-induced cell death relies on SLFN11-dependent cleavage of distinct type II tRNAs. Li M, et al. Nature Structural & Molecular Biology, 2018
