Gene Expression Array Service

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Arraystar offers the complete service based on Agilent whole genome microarrays, from sample to publishable data!

Benefits

• Our expertise in the microarray experiments and high array technical quality are the key to the success of gene expression profiling.

• Our service is based on the most powerful platform in this field, Agilent, offering variety of choices in array content, density and analysis tools.

The gene expression arrays that are most often selected by our customers include:

Microarray Species Format Probe length Coverage
Whole Human Genome Human 4 * 44K 60-mer 27,958
Whole Mouse Genome Mouse 4 * 44K 60-mer 39,430
Whole Rat Genome Rat 4 * 44K 60-mer 26,930

Service NameFormatPrice
Gene Expression Array Service 4*44K
Gene Expression Array Service 8*60K

Arraystar's bioinformatics team has extensive experience in analyzing gene expression array data. We provide comprehensive data analyses, including:

• Raw Data Files

• Summary Report

• Box Plot, Scatter Plot and Hierarchical Clustering

• Differentially Expressed Gene Screening

• GO Analysis and Pathway Analysis(Fig.1)

GO_EnrichmentScore

Pathway_EnrichmentScore       
Fig.1 GO and Pathway Analysis.  Significant GO terms/Pathways of differentially expressed gene. A bar plot is generated from the top 10 GO terms/Pathways containing the largest fold enrichment of differentially expressed genes. The plot gives a more intuitive view of the significant GO terms/Pathways.

Please refer to Sample Submission for details in how to get your project started.

• RNA isolation (Optional)

• RNA QC

• cDNA synthesis

• Target preparation by labeling with Cy3

• Array hybridization, washing, and scanning

• Data extraction, analysis and summarization

Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic ß Cell Death and May Contribute to Type 1 Diabetes Development. Guay C,et al. Cell metabolism, 2018

Osteoblast-secreted factors mediate dormancy of metastatic prostate cancer in the bone via activation of the TGFßRIII-p38MAPK-pS249/T252RB pathway. Yu-Lee L Y, et al. Cancer Research, 2018

MicroRNA-Mediated Dynamic Bidirectional Shift between the Subclasses of Glioblastoma Stem-like Cells. Rooj A K, et al. Cell Reports, 2017

MicroRNA Signatures and Molecular Subtypes of Glioblastoma: The Role of Extracellular Transfer. Godlewski J,  et al. Stem Cell Reports, 2017

Bmal1 is required for beta cell compensatory expansion, survival and metabolic adaptation to diet-induced obesity in mice. Rakshit K, et al. Diabetologia, 2016

FOXP3 promotes tumor growth and metastasis by activating Wnt/ß-catenin signaling pathway and EMT in non-small cell lung cancer. Yang S,et al. Molecular Cancer, 2017

Long noncoding RNA CRNDE stabilized by hnRNPUL2 accelerates cell proliferation and migration in colorectal carcinoma via activating Ras/MAPK signaling pathways. Jiang H, et al. Cell Death & Disease, 2017

In vitro expansion impaired the stemness of early passage mesenchymal stem cells for treatment of cartilage defects. Jiang T, et al. Cell Death & Disease, 2017

Circular RNAs as novel regulators of ß-cell functions in normal and disease conditions. Stoll L, et al. Molecular Metabolism, 2017

PMP22 Regulates Self-Renewal and Chemoresistance of Gastric Cancer Cells. Cai W, et al. Molecular Cancer Therapeutics, 2017

Competing endogenous RNA expression profiling in pre-eclampsia identifies hsa_circ_0036877 as a potential novel blood biomarker for early pre-eclampsia. Hu X, et al. Clinical epigenetics, 2018

Differential Expression of MiR-106b-5p and MiR-200c-3p in Newly Diagnosed Versus Chronic Primary Immune Thrombocytopenia Patients Based on Systematic Analysis. Qian C, et al. Cellular Physiology and Biochemistry, 2018

miR-130a and miR-212 Disrupt the Intestinal Epithelial Barrier through Modulation of PPAR? and Occludin Expression in Chronic Simian Immunodeficiency Virus–Infected Rhesus Macaques. Kumar V, et al. The Journal of Immunology, 2018

ABCF2, an Nrf2 target gene, contributes to cisplatin resistance in ovarian cancer cells. L Bao,  et al. Molecular Carcinogenesis, 2017

Differentially expressed host long intergenic noncoding RNA and mRNA in HIV-1 and HIV-2 infection. Biswas S, et al. Scientific Reports, 2018

miR-17-92 Cluster Promotes Cholangiocarcinoma Growth: Evidence for PTEN as Downstream Target and IL-6/Stat3 as Upstream Activator. H Zhu, et al. The American Journal of Pathology, 2014

Sucrose non-fermenting related kinase enzyme is essential for cardiac metabolism. Cossette SM, et al. Biol Open, 2014

Bifunctional enzyme SpoT is involved in the clarithromycin tolerance of Helicobacter pylori by up-regulating the transporters HP0939, HP1017, HP0497, and HP0471. Geng X,et al. Antimicrobial Agents and Chemotherapy, 2017

MeCP2, a target of miR-638, facilitates gastric cancer cell proliferation through activation of the MEK1/2-ERK1/2 signaling pathway by upregulating GIT1. Zhao L Y, et al. Oncogenesis, 2017

Chronic occupational exposure to arsenic induces carcinogenic gene signaling networks and neoplastic transformation in human lung epithelial cells. Todd A. Stueckle, et al. Toxicology and Applied Pharmacology, 2012