• Description
  • Highlights
  • Database
Product NameCatalog NoDescriptionFormatPrice
Human LncRNA Expression Microarray V4.0 AS-LNC-H-V4.0 20,730 mRNAs and 40,173 LncRNAs 8*60K

Arraystar is a pioneer in LncRNA microarrays to systematically profile lncRNAs together with mRNAs on the same chip. To date, these microarrays have been an empowering tool and invaluable resource in LncRNA research touting many high impact publications. To incorporate rapid scientific advances and new data, Arraystar has now released new Human Version 4.0.

The Arraystar Human LncRNA Expression Microarray V4.0 contains the following two important changes from V3.0:

1. The best contents: the Gold Standard LncRNAs, Reliable LncRNAs and protein coding mRNAs

Unlike protein coding genes, publically available lncRNAs are often scantily annotated, partial in scope and scattered in collection. Arraystar maintains high quality proprietary transcriptome and lncRNA databases to extensively collect lncRNAs through our lncRNA discovery pipelines, external data sources, and knowledge-based mining of scientific publications. Arraystar Human LncRNA Microarray V4.0 has a total of 40,173 lncRNAs in two major lncRNA collections, 7,506 for Gold Standard LncRNAs and 32,667 Reliable LncRNAs, from more than 47 Tb worth of RNA-seq data and all major public databases and repositories, such as Refseq, USCS Known Genes, GENCODE, lincRNA catalogs, lncRNAdb, T-UCRs, RNAdb, NRED, and scientific publications.  

2. Towards systematic and functional annotation of LncRNAs

Importantly, systematic and detailed lncRNA annotations, subclassification and analyses are packaged in our sample-to-results microarray services to gain insight into the complex biology of lncRNAs. All the reported LncRNAs involved in biological processes, such as apoptosis, differentiation and development, or associated with human diseases, such as cancers, neurodegenerative diseases, and cardiovascular diseases, are comprehensively annotated and cross referenced. This rich source of information helps to unravel functional roles and molecular mechanisms of the LncRNAs.  

The Arraystar Human Expression Microarray V4.0 is available only through the LncRNA Expression Microarray service at Arraystar.

• The most sensitive and best technology to profile lncRNA expression. Better than RNA-seq for lncRNA profiling as lncRNAs are often at lower abundance.

• The most up-to-date, extensive and high quality array contents to include the Gold-Standard LncRNAs, Reliable LncRNAs and mRNAs certified with proteins on the same chip.

• Systematic and functional lncRNA annotations and analyses to incorporate advances in lncRNA research and are complete with genomic information, subclassification, and potential regulatory mechanisms, to gain insights into the complex lncRNA biology. LncRNAs associated with biological processes or human diseases are annotated and referenced.

• Unambiguous transcript-specific probes for accurate and reliable detection and quantification of transcript isoforms.

• A wealth of information for co-expressional and correlational studies of non-coding regulatory lncRNAs with protein coding mRNAs.

Data Sources
Composition of the Arraystar Human LncRNA Expression Microarray V4.0

Specifications

Total number of distinct probes 60,903
Probe selection region Specific exon or splice junction along the entire length of the transcript
Probe specificity Transcript-specific
Labeling method cRNAs are labeled along the entire length without 3’ bias, even for degraded RNA at low amount.
Total LncRNAs 40,173
Gold Standard LncRNAs 7,506
Reliable LncRNAs 32,667
Transcribed pseudogenes 699
Protein coding mRNAs 20,730
LncRNA sources Databases current in 2015:
Refseq, UCSC, GENCODE, LncRNAdb, RNAdb, NRED, lincRNA catalogs (Cabili et al 2011, Clark et al 2015, Iyer et al 2015), ENCODE CAGE Clusters, PolyA-seq, deep RNA-Seq and capture seq data repositories.
Arraystar LncRNA collection pipelines. Literature:
Scientific publications up to 2015.
mRNA sources Refseq, GENCODE in conjunction with UniProt


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