• Description
  • Workflow
  • Bioinformatics Analysis
  • Publications
Service NameFormatPrice
Gene Expression Array Service 4*44K
Gene Expression Array Service 8*60K

Gene expression profiling is a technology that utilizes microarrays to analyze genome-wide profiling of gene expression. Arraystar's gene expression profiling service is based on the most powerful platform in this field, Agilent. The availability of the array services from the platform offers our customers variety of choices in array content, density and analysis tools. The gene expression arrays that are most often selected by our customers include:

Agilent Whole Genome Expression Arrays

Microarray Species Format Probe length Coverage Probes /target gene
Whole Human Genome Human 4 * 44K 60-mer 27,958 1
Whole Mouse Genome Mouse 4 * 44K 60-mer 39,430 1
Whole Rat Genome Rat 4 * 44K 60-mer 26,930 1

Please refer to Sample Submission for details in how to get your project started.

• RNA isolation (Optional)

• RNA QC

• cDNA synthesis

• Target preparation by labeling with Cy3

• Array hybridization, washing, and scanning

• Data extraction, analysis and summarization

Arraystar's bioinformatics team has extensive experience in analyzing gene expression array data. We provide two levels of analysis: standard and advanced.

Standard Data Analysis

• Raw Data Files

• Summary Report

• Box Plot, Scatter Plot and Hierarchical Clustering

• Differentially Expressed Gene Screening

• GO Analysis (Fig.1) and Pathway Analysis

gene_expression
Fig.1 GO Analysis (Standard Data Analysis).  Significant GO terms of differentially expressed gene. A bar plot is generated from the top 10 GO terms containing the largest fold enrichment of differentially expressed genes. The plot gives a more intuitive view of the significant GO terms.

Bmal1 is required for beta cell compensatory expansion, survival and metabolic adaptation to diet-induced obesity in mice.Rakshit K, et al.Diabetologia,2016

ABCF2, an Nrf2 target gene, contributes to cisplatin resistance in ovarian cancer cells. L Bao, et al. Molecular Carcinogenesis?, 2017

Bifunctional enzyme SpoT is involved in the clarithromycin tolerance of Helicobacter pylori by up-regulating the transporters HP0939, HP1017, HP0497, and HP0471. Geng X,et al. Antimicrobial Agents and Chemotherapy, 2017

Silencing of CD40 in vivo reduces progression of experimental atherogenesis through an NF-?B/miR-125b axis and reveals new potential mediators in the pathogenesis of atherosclerosis. Hueso M, et al. Atherosclerosis?, 2016

Gene expression profiling and bioinformatics analysis in 16HBE cells treated by chromium (VI). Hu G, et al. Toxicology Letters?, 2016

Altered metabolic activity in the developing brain of rats predisposed to high versus low depression-like behavior CR McCoy, et al. Neuroscience, 2016

Coding and non-coding gene regulatory networks underlie the immune response in liver cirrhosis. Gao B, et al. PloS one, 2017 

Regulation of membrane fixation and energy production/conversion for adaptation and recovery of ZnO nanoparticle impacted Nitrosomonas europaea, Wu J,et al. Applied Microbiology and Biotechnology, 2017 

Pleiotropic Effect of a High Resolution Mapped Blood Pressure QTL on Tumorigenesis.Cheng X, et al.PLoS ONE,2016

Gene expression profiles of human lung epithelial cells chronically exposed to single-walled carbon nanotubes. D Chen, et al. Nanoscale Research Letters, 2015

Genetic predisposition to high anxiety-and depression-like behavior coincides with diminished DNA methylation in the adult rat amygdala. McCoy C R,  et al. Behavioural Brain Research, 2016

Global expression profile of tumor stem-like cells isolated from MMQ rat prolactinoma cell. Z Su, et al. Cancer Cell International, 2017

Identification of gene signatures regulated by carvedilol in mouse heart. Jian-peng Teoh, et al.Physiol Genomics, 2016.

Transcriptome reveals the overexpression of a kallikrein gene cluster (KLK1/3/7/8/12) in the Tibetans with high altitude-associated polycythemia. International Journal of Molecular Medicine. 2016

Prognostic Significance of MAGE-A11 in Esophageal Squamous Cell Carcinoma and Identification of Related Genes Based on DNA Microarray. Sang M, et al. Archives of Medical Research, 2016

Role of MAPK/ERK signal pathway in recurrent miscarriage patients by case-control analysis. Wang Y,et al. Int J Clin Exp Pathol, 2016

Genome-scale transcriptional analysis reveals key genes associated with the development of type II diabetes in mice. Zhang Y, et al. Experimental and Therapeutic Medicine, 2017

Whole genome expression microarray analysis of highly versus poorly tumorigenic murine melanoma cell lines provides insights into factors that regulate tumor growth, metastasis, and immunogenicity. Kristian Michael Hargadon,et al.  Frontiers in Immunology, 2015

miR-17-92 Cluster Promotes Cholangiocarcinoma Growth: Evidence for PTEN as Downstream Target and IL-6/Stat3 as Upstream Activator. H Zhu, et al. The American Journal of Pathology, 2014

Sucrose non-fermenting related kinase enzyme is essential for cardiac metabolism. Cossette SM, et al. Biol Open, 2014

Global Effect of Inauhzin on Human p53-Responsive Transcriptome. Jun-Ming Liao, et al. PLoS ONE, 2012

Chronic occupational exposure to arsenic induces carcinogenic gene signaling networks and neoplastic transformation in human lung epithelial cells. Todd A. Stueckle, et al. Toxicology and Applied Pharmacology, 2012

MeCP2 promotes gastric cancer progression through regulating FOXF1/Wnt5a/ß-Catenin and MYOD1/Caspase-3 signaling pathways. Zhao L, et al. EBioMedicine, 2017