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Fig 1. RNA-seq relies on circular junction sequences for circRNA detection (top), which are too low in abundance for reliable and accurate quantification (bottom).
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Latest About Circular RNA in Cancer
Liver Cancer
CircGPR137B/miR-4739/FTO feedback loop suppresses tumorigenesis and metastasis of hepatocellular carcinoma. Liu L, et al. Molecular Cancer, 2022
Prostate Cancer
Hsa_circ_0003258 promotes prostate cancer metastasis by complexing with IGF2BP3 and sponging miR-653-5p. Yu Y Z, et al. Molecular Cancer, 2022
CircPDE5A regulates prostate cancer metastasis via controlling WTAP-dependent N6-methyladenisine methylation of EIF3C mRNA. Ding L, et al.Journal of Experimental & Clinical Cancer Research, 2022
Colorectal Cancer
The N6-methyladenosine modification of circALG1 promotes the metastasis of colorectal cancer mediated by the miR-342-5p/PGF signalling pathway. Lin C, et al.Molecular Cancer, 2022
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