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CircRNA Epitranscriptomic Array Service

Title Author Journal Year
N6-methyladenosine hypomethylation of circGPATCH2L regulates DNA damage and apoptosis through TRIM28 in intervertebral disc degeneration Chen Z, et al Cell Death & Differentiation 2023
YTHDC1 maintains trophoblasts function by promoting degradation of mA6-modified circMPP1 Wang D, et al Biochemical Pharmacology 2023
Exploring CircRNA N6-methyladenosine in human rheumatoid arthritis: Hyper-methylated hsa_circ_0007259 as a potential biomarker and its involvement in the hsa_circ_0007259/ hsa_miR-21-5p/STAT3 axis Luo H, et al International Immunopharmacology 2023
m6A modifications of circular RNAs in ischemia-induced retinal neovascularization Zhou Y, et al International Journal of Medical Sciences 2023
METTL14-mediated m6A modification of circORC5 suppresses gastric cancer progression by regulating miR-30c-2-3p/AKT1S1 axis Fan H N, et al. Molecular Cancer  2022
The Combined Effects of circRNA Methylation Promote Pulmonary Fibrosis Wang S, et al. American Journal of Respiratory Cell and Molecular Biology 2022
m6 A-modified circFOXK2 targets GLUT1 to accelerate oral squamous cell carcinoma aerobic glycolysis Cui Y,et al Cancer Gene Therapy 2022
Chronic Hexavalent Chromium Exposure Up-regulates the RNA Methyltransferase METTL3 Expression to Promote Cell Transformation, Cancer Stem Cell-like Property and Tumorigenesis Wang Z, et al. Toxicological Sciences 2022
High-throughput microarray reveals the epitranscriptome-wide landscape of m6A-modified circRNA in oral squamous cell carcinoma Zhao W,et al BMC genomics 2022
Expression profiling of N6-methyladenosine modified circRNAs in acute myeloid leukemia Issah M A, et al. Biochemical and Biophysical Research Communications 2022
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mRNA&LncRNA Epitranscriptomic Array Service

Title Author Journal Year
Multigenerational paternal obesity enhances the susceptibility to male subfertility in offspring via Wt1 N6-methyladenosine modification Xiong Y W,et al Nature Communications 2024
METTL3-Mediated m6A Modification Regulates the Osteogenic Differentiation through LncRNA CUTALP in Periodontal Mesenchymal Stem Cells of Periodontitis Patients Chen X, et al Stem Cells International 2024
RNA N6-methyladenosine modification based biomarkers for absorbed ionizing radiation dose estimation Chen H, et al Nature Communications 2023
N6 -methyladenosine promotes aberrant redox homeostasis required for arsenic carcinogenesis by controlling the adaptation of key antioxidant enzymes Zhao T, et al Journal of Hazardous Materials 2023
N6-methyladenosine demethylase FTO regulates synaptic and cognitive impairment by destabilizing PTEN mRNA in hypoxic ischemic neonatal rats Deng J, et al Cell Death & Disease 2023
High glucose induces tau hyperphosphorylation in hippocampal neurons via inhibition of ALKBH5-mediated Dgkh m6 A demethylation: a potential mechanism for diabetic cognitive dysfunction Qu M, et al Cell Death & Disease 2023
GLIS1 alleviates cell senescence and renal fibrosis through PGC1-α mediated mitochondrial quality control in kidney aging Xu L, et al Free Radical Biology and Medicine 2023
WTAP-Mediated N6-Methyladenosine of RNAs Facilitate the Pathophysiology of Atopic Dermatitis Tan L, et al Journal of Investigative Dermatology 2023
m6A reader IGF2BP2 promotes lymphatic metastasis by stabilizing DPP4 in papillary thyroid carcinoma Wang W, et al Cancer Gene Therapy 2023
METTL3/IGF2BP3 axis inhibits tumor immune surveillance by upregulating N6-methyladenosine modification of PD-L1 mRNA in breast cancer Wan W, et al. Molecular Cancer  2022
N6 -methyladenosine plays a dual role in arsenic carcinogenesis by temporal-specific control of core target AKT1 Zhao T,et al Journal of Hazardous Materials 2022
WTAP-mediated m6A modification of lncRNA DIAPH1-AS1 enhances its stability to facilitate nasopharyngeal carcinoma growth and metastasis Li Z X, et al. Cell Death & Differentiation 2022
N6 -methyladenosine plays a dual role in arsenic carcinogenesis by temporal-specific control of core target AKT1 Zhao T,et al Journal of Hazardous Materials 2022
PGE2‐EP3 axis promotes brown adipose tissue formation through stabilization of WTAP RNA methyltransferase Tao X, et al. The EMBO Journal 2022
METTL3 promotes colorectal carcinoma progression by regulating the m6A–CRB3–Hippo axis Pan J, et al. Journal of Experimental & Clinical Cancer Research 2022
METTL3 modulates m6A modification of CDC25B and promotes head and neck squamous cell carcinoma malignant progression Guo Y,  et al. Experimental Hematology & Oncology 2022
Long Noncoding RNA and mRNA m6A Modification Analyses of Periodontal Ligament Stem Cells from the Periodontitis Microenvironment Exposed to Static Mechanical Strain Sun W,et al Stem Cells International 2022
ALKBH5 regulates cardiomyocyte proliferation and heart regeneration by demethylating the mRNA of YTHDF1 Han Z, et al.  Theranostics 2021
RBM15 facilitates laryngeal squamous cell carcinoma progression by regulating TMBIM6 stability through IGF2BP3 dependent Wang X, et al.  Journal of Experimental & Clinical Cancer Research 2021
ALKBH5 suppresses tumor progression via an m 6 A-dependent epigenetic silencing of pre-miR-181b-1/YAP signaling axis in osteosarcoma Yuan Y, et al.  Cell Death & Disease 2021
RBM15-mediated N6-methyladenosine modification affects COVID-19 severity by regulating the expression of multitarget genes Meng Y, et al.  Cell Death & Disease 2021
ALKBH5-mediated m6A mRNA Methylation Governs Human Embryonic Stem Cell Cardiac Commitment Han Z, et al.  Molecular Therapy-Nucleic Acids 2021
N6-methyladenosine (m6A) methyltransferase WTAP accelerates the Warburg effect of gastric cancer through regulating HK2 stability Yu H, et al.  Biomedicine & Pharmacotherapy 2020
Bioinformatics analysis integrating metabolomics of m6A RNA microarray in intervertebral disc degeneration Wang X, et al.  Epigenomics 2020
Fusarium infection alters the m6A-modified transcript landscape in the cornea Jianzhang Hu, et al.  Experimental Eye Research 2020
Epitranscriptome of the ventral tegmental area in a deep brain-stimulated chronic unpredictable mild stress mouse model Song N, et al.  Translational Neuroscience 2020
Transient Focal Ischemia Significantly Alters the m6A Epitranscriptomic Tagging of RNAs in the Brain Chokkalla A K, et al.  Stroke 2019
m6A methylation of precursor-miR-320/RUNX2 controls osteogenic potential of bone marrow-derived mesenchymal stem cells Yan G, et al.  Molecular Therapy-Nucleic Acids 2019
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