Small RNAs, including miRNAs and tRNA-derived small RNAs (tsRNAs), harbor a diversity of RNA modifications such as o8G, m7G, m6A, Ψ, and m5C. These modifications modulate small RNA activities in pathophysiological conditions. Quantitative profiling of modified small RNA levels and stoichiometry provides opportunities to uncover their new functional roles and use them as disease biomarkers. Arraystar Small RNA Modification Arrays are the best current technology for the profiling challenges.
This webinar covers:
- Small RNA modifications in biological functions and diseases
- Small RNA modifications as biomarkers
- Challenges of small RNA modification profiling
- Solution to small RNA modification profiling with microarrays