Downstream-of-gene (DoG) RNAs are the RNAs transcribed continuously beyond the host gene transcription termination sites. They occur in ~10% protein coding genes in the cells, with typical sizes between 5~200 kb. Due to their extended lengths, some DoGs can further produce DoG-derived chimera RNAs and circular RNAs. Recent studies found DoG RNAs have many unique properties and important biological functions. They are often associated with cancers and diseases.
This webinar will cover:
- What DoG RNAs are
- DoG RNA Biogenesis
- DoG-derived chimera RNAs and circular RNAs
- DoG functions and diseases
- DoG RNA profiling by Arraystar DoG RNA microarray
- DoG RNA research roadmap