Arraystar scientists have developed a full range of powerful microarrays for evaluating the global expression levels of LncRNAs in humans, mice, and rats. In 2009, we launched the Arraystar LncRNA Microarray V1.0 - the first commercial microarray for expression profiling of LncRNAs and mRNAs side by side. This ground-breaking microarray made us the industry leader in LncRNA research. Following the popularity of this innovative scientific tool, the Arraystar LncRNA Microarray V2.0 was released in March 2011, quickly becoming our best-selling product and contributing greatly to driving the heightened interest in this intriguing group of non-coding RNAs.
Now, Arraystar is very proud to introduce our third-generation LncRNA microarray, the Arraystar Human LncRNA Microarray V3.0. Slated for release in early 2013, version 3.0 will provide a newly-updated and stringent LncRNA collection, as well as additional non-coding RNAs of interest. In addition, the Arraystar Human LncRNA Microarray V3.0 features an enhancement of our concise and scientific LncRNA subgroup and classification.
|
Microarray |
Species |
Format |
Detected LncRNAs |
| Arraystar Human LncRNA Array V3.0.pdf NEW! | Human | 8 * 60K | LncRNAs(~30,600)+coding genes (~26,100) |
|
Human |
8 * 60K |
LncRNAs(~33,000)+coding genes (~30,200) | |
|
Mouse |
8 * 60K |
LncRNAs(~31,423)+coding genes(~25,376) | |
|
Mouse |
4 * 44K |
LncRNAs(stringent ~13,800) + coding genes (~19,500) | |
|
Rat |
4 * 44K |
LncRNAs(~9,300)+coding genes (~15,200) |
Arraystar's specially-designed LncRNA microarrays are available only through our LncRNA microarray service. We provide full-service LncRNA microarray profiling, from sample preparation to in-depth data analysis. Our step-by-step quality controls are designed to ensure you get the most reliable results. Just send us your samples, and we'll do the rest!
Recent Publications Citing Our LncRNA Microarry Service
Repression of the Long Noncoding RNA-LET by Histone Deacetylase 3 Contributes to Hypoxia-Mediated Metastasis.
Yang F, et al. Mol Cell, 2013
LncRNA-LALR1 accelerates hepatocyte proliferation during liver regeneration by activating Wnt/¦Â-Catenin signaling.
Xu D, et al. Hepatology, 2013
Sinomenine Protests against Lipopolysaccharide-Induced Acute Lung Injury in Mice via Adenosine A2A Receptor Signaling.
Jun Li, et al. PLoS ONE, 2013
HBx-related lncRNA Dreh inhibits hepatocellular carcinoma metastasis by targeting the intermediate filament protein vimentin.
Huang JF, et al. Hepatology. 2012
Effect of Focal Ischemia on Long Noncoding RNAs.
Description of Services
Please refer to Sample Submission for details in how to get your project started.
• RNA isolation (Optional)
• RNA QC
• cDNA synthesis
• Target preparation by labeling with Cy3
• Array hybridization, washing, and scanning
• Data extraction, analysis and summarization
Bioinformatics Analysis
Arraystar's experienced scientists have intimate knowledge of the LncRNA microarray platform and are experts in the analysis and interpretation of LncRNA profiling data. This familiarity enables us to employ the most robust methods for normalization and data analysis including subgroup classification.
|
2 Fold Up/Down-regulated LncRNAs Pass t-test (Group 1 vs. Group 2 ) | |||||||
|
|
P-value, Fold Change and Regulation |
Annotation | |||||
|
Probe Name |
P-value
<0.05 |
FC Absolute>2 |
Regulation |
Genbank Accession |
Gene Symbol |
Source |
Relationship |
|
ASLNC01537 |
0.0012 |
4.1664 |
Up |
NR_003716 |
HOTAIR |
Refseq |
Intergenic |
|
ASLNC01507 |
0.0236 |
2.6177 |
Up |
NR_023920 |
WT1AS |
Refseq |
Bidirection |
|
ASLNC02828 |
0.0001 |
2.5284 |
Down |
HIV2506 |
_ |
RNAdb |
Antisense_
intron |
|
ASLNC12685 |
0.0018 |
3.0126 |
Down |
uc002zdu |
LOC284837 |
UCSC_
knowngene |
Others |
Table 1. Differentially expressed LncRNAs screening. Differentially expressed LncRNAs (Fold change>2, p-value<0.05) in Group1 vs Group2. In column "Regulation", "Up" indicates up-regulated, "Down" indicates down-regulated.
Fig.1 Visualization of LncRNAs of Interest. Our LncRNAs microarray results can be visualized using the UCSC genome browser. The figure indicates both the magnitude and direction of the expression level changes of LncRNAs.
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