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aCGH Service

 

aCGH (microarray-based comparative genomic hybridization) is a microarray-based technique used to identify and characterize DNA copy number variations across the genome. Arraystar provides aCGH service from sample to data. The ultra-high density 2.1 million feature arrays offer unprecedented data resolution for CGH analysis. They enable genome-wide detection of copy number variants (CNVs) down to ~5kb in size and analysis of targeted regions at the exon-level resolution.
 
We provide services for all the aCGH arrays available from Roche-NimbleGen. The aCGH arrays that are most often selected by our customers include:
Species
Format
Probe Median Spacing
Genome Build
Description
Human
1 * 2.1M
1,169bp
hg18
Whole genome
Human
3 * 720K
4,750bp
hg18
Whole genome
Human
1 * 385K
20-575bp
hg18
Chr. specific
Mouse
3 * 720K
3,537bp
Mm9
Whole genome
 
Description of Service
Please refer to Sample Submission for details in how to get your project started.
1.  Incoming gDNA QC
2.  Sonication to shear gDNA
3.  Target preparation by labeling with Cy3/5
4.  Array hybridization, washing, and scanning
5.  Data extraction, analysis and summarization
 

 

Service Guide

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